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Vitiligo ndimkhalidwe wodziyimira wokha momwe zimayambira zoyera pakhungu. Ku India, kuchuluka kwa vitiligo kumachokera ku 0.25 mpaka 2.5%. Rajasthan ndi Gujarat ndizofala kwambiri pamtunduwu ^[1] .

Kodi Vitiligo ndi Chiyani?

Ma Melanocyte, omwe amapanga khungu, amathandizira khungu lanu, mtundu wa maso, ndi utoto wa tsitsi. Ma melanocytes akawonongedwa, zigamba zoyera zimawoneka pakhungu, lotchedwa vitiligo ^[ziwiri] . Vitiligo imakhudza mbali zina za thupi monga manja, nkhope, khosi, mawondo, mapazi ndi zigongono.

Vitiligo siyopatsirana ndipo imachitika chifukwa cha majini, zinthu zachilengedwe kapena kusowa kwa michere.

Chizindikiro choyamba cha vitiligo ndi chigamba chomwe chimawonekera pang'onopang'ono pakhungu ndipo tsitsi limasanduka loyera. Zizindikiro zina ndi kuyeretsa tsitsi msanga pamutu panu, nsidze, ndevu ndi nsidze, kutayika kwa utoto m'matumba omwe amalowa mkati mwa mphuno ndi pakamwa panu, komanso kutayika kwa mtundu mu diso.

Chithandizo cha vitiligo chimatenga nthawi kuti chiwonetse zotsatira zabwino. Kaya ndi mankhwala ochiritsira kapena achilengedwe, zimatha kutenga miyezi 6 mpaka zaka ziwiri.

Kuyambira kale, mitundu yosiyanasiyana ya zitsamba yakhala ikugwiritsidwa ntchito pochiza vitiligo.

1. Ginkgo biloba

M'zaka zingapo zapitazi, zowonjezera za ginkgo biloba zakhala zikugwiritsidwa ntchito pochiza vitiligo chifukwa ginkgo biloba ili ndi anti-inflammatory, immunomodulatory, ndi antioxidant. Kafukufuku akuwonetsa kuti ginkgo biloba imayang'anira ntchito ya vitiligo ndipo imapangitsa kusintha kwa ma macule oyera ngati agwiritsidwa ntchito ndi mankhwala ena monga phototherapies ndi corticosteroids ^[3] . Kafukufuku wina akuwonetsanso kugwira ntchito kwa mankhwala azitsamba mukamayendetsa nokha ^[4] .

Zotsatira zakubwezeretsanso zimasiyana malinga ndi zinthu monga mitundu yosiyanasiyana ya zotumphukira za ginkgo biloba, kutalika kwa chithandizo, ndi kuchuluka kwa mankhwala patsiku.

Mankhwalawa amapangidwa piritsi ndipo kuchuluka kwake tsiku ndi tsiku ndi 120 mg patsiku. Ayenera kumwedwa pakamwa kamodzi kapena katatu tsiku lililonse kwa miyezi yopitilira itatu.

2. Mphepo yamkuntho

Turmeric imakhala ndi polyphenol yomwe imadziwika kuti curcumin yomwe imadziwika kuti imakhala ndi antioxidant, anti-inflammatory, antiviral, antibacterial, antiproliferative ndi antifungal. Malinga ndi kafukufuku waposachedwa, kirimu cha tetrahydrocurcumide chagwiritsidwa ntchito ndi nb - UVB yothandizira mankhwala a vitiligo ndipo zotsatira zake zikuwonetsa kusintha kwabwino ^[5] .

3. Tiyi wobiriwira

Masamba a tiyi obiriwira ali ndi polyphenol antioxidants ambiri. Zowonjezera za tsamba la tiyi wobiriwira zimagwira ntchito ngati anti-yotupa, antioxidant, ndi ma immunomodulatory agents omwe atsimikiziridwa kuti ndi othandiza pochiza vitiligo poletsa kupsyinjika kwa okosijeni ya gawo la melanocyte ^[6] .

Tingafinye ya tiyi wobiriwira imatha kutumizidwa pakamwa komanso pamutu.

4. Capsaicin

Tsabola wa tsabola mumakhala mankhwala omwe amatchedwa capsaicin omwe amakhala ndi antioxidant komanso anti-inflammatory omwe amagwira ntchito ngati mankhwala a vitiligo ^[7] .

5. Aloe vera

Aloe vera amatha kuthana ndi matenda osiyanasiyana akhungu kuphatikiza matenda amtundu wa pigment chifukwa ali ndi mavitamini a antioxidant monga vitamini A, vitamini C, vitamini B12 ndi folic acid. Kutulutsa kwa Aloe vera kumakhalanso ndi zinc, mkuwa, ndi chromium zomwe zitha kuthandizira kusintha khungu ^[8] .

Chotsani gel osamba ya tsamba la aloe vera ndikuigwiritsa ntchito kudera lomwe lakhudzidwa.

6. Muskmelon

Kutulutsa kwa Muskmelon kuli kodzaza ndi ma antioxidants omwe amalepheretsa kumangidwanso kwa melanocytes chifukwa cha kupsinjika kwa oxidative. Kafukufuku adawonetsa kufunikira kwa kapangidwe ka gel kokhala ndi phenylalanine, muskmelon Tingafinye, ndi acetylcysteine mu vitiligo. Chithandizocho chinapitilira kwa masabata a 12 ndipo 75% ya kubwezeretsedwaku idawonetsedwa mwa odwala ^[9] .

7. Picrorhiza kurroa

Picrorhiza kurroa, wotchedwanso kutki kapena kutaki, ndi mankhwala omwe amapezeka ku Himalaya. Lili hepatoprotective, antioxidant ndi immunomodulatory katundu. Kafukufuku adawonetsa kuthekera kwakukulu kwa Picrorhiza kurroa komwe amagwiritsidwa ntchito limodzi ndi phototherapy yothandizira vitiligo. Amayendetsedwa kawiri patsiku pakamwa kwa miyezi itatu ^[10] .

8. Pyrostegia Venusta

Pyrostegia venusta ndi zitsamba zomwe zimagwiritsidwa ntchito pochiza vitiligo. Lili ndi antioxidant, anti-inflammatory ndi melanogenic. Amapezeka ku Southern Brazil, kumene mankhwala opangira mankhwala amagwiritsidwa ntchito pochiza vitiligo ^{[khumi ndi chimodzi]} .

9. Khellin

Kuyambira kale ku Aigupto, khellin wakhala akugwiritsidwa ntchito ngati mankhwala azitsamba ochiritsira matenda ambiri monga miyala ya impso, matenda amtima, vitiligo, bronchial asthma ndi psoriasis. Khellin wogwiritsidwa ntchito limodzi ndi UVA phototherapy yawonetsedwa kuti ndi othandiza pochiza vitiligo. Khellin amagwira ntchito polimbikitsa kuchuluka kwa melanocytes ndi melanogenesis ^[12] .

10. Polypodium leucotomos

Polypodium leucotomos ndi fern wam'malo otentha omwe amapezeka ngati makapisozi ndi zonona. Amapezeka kumadera otentha ndi madera otentha a America. Zotulutsa za polypodium leucotomos ndizotchuka chifukwa cha antioxidant komanso photoprotective ndipo amagwiritsidwa ntchito pochiza matenda osiyanasiyana akhungu. Polypodium leucotomos yakhala ikugwiritsidwa ntchito limodzi ndi phototherapy mu odwala vitiligo ^[13] .

Zindikirani: Musanagwiritse ntchito mankhwala achilengedwe awa, ndibwino kukaonana ndi dokotala kuti akuthandizeni mlingo woyenera komanso kugwiritsa ntchito moyenera momwe zingakhalire ndi zovuta zomwe simukuzidziwa.

Onani Zolemba Pazolemba

[1]Vora, R. V., Patel, B. B., Chaudhary, A.H, Mehta, M. J., & Pilani, A. P. (2014). Kafukufuku Wachipatala wa Vitiligo Kumadera Akumidzi ku Gujarat. Buku laku India lonena za mankhwala am'magulu: kutulutsa kovomerezeka kwa Indian Association of Preventive & Social Medicine, 39 (3), 143-146.
[ziwiri]Yamaguchi, Y., & Kumva, V. J. (2014). Ma Melanocyte ndi matenda awo. Maganizo a Cold Spring Harbor mu zamankhwala, 4 (5), a017046.
[3]Cohen, B. E., Elbuluk, N., Mu, E. W., & Orlow, S. J. (2015). Njira zina zochiritsira vitiligo: kuwunika. Magazini aku America azachipatala, 16 (6), 463-474.
[4]Parsad, D., Pandhi, R., & Juneja, A. (2003). Kuchita bwino kwa pakamwa Ginkgo biloba pochiza vitiligo yocheperako, yocheperako. Clinical and Experimental Dermatology: Kafukufuku wa khungu, 28 (3), 285-287.
[5]Asawanonda, P., & Klahan, S. O. (2010). Kirimu cha Tetrahydrocurcuminoid kuphatikiza phototherapy yocheperako ya UVB ya vitiligo: kafukufuku woyambirira wokhazikika. Photomedicine ndi opareshoni ya laser, 28 (5), 679-684.
[6][Nkhani yaulere ya PMC] [Adasankhidwa] [Cross Ref] Jeong YM, Choi Y. G., Kim D., Park S., Yoon J. A., Kwon S., B. & ... & Park K. C. (2005). Cytoprotective zotsatira za tiyi wobiriwira komanso quercetin motsutsana ndi kupsyinjika kwa hydrogen peroxide-komwe kumayambitsa kupsinjika kwa okosijeni. Zakale za kafukufuku wamafuta, 28 (11), 1251.
[7]Becatti, M., Prignano, F., Fiorillo, C., Pescitelli, L., Nassi, P., Lotti, T., & Taddei, N. (2010). Kutenga nawo gawo kwa njira ya Smac / DIABLO, p53, NF-kB, ndi MAPK mu apoptosis ya keratinocytes kuchokera ku khungu la vitiligo khungu: zoteteza za curcumin ndi capsaicin. Antioxidants & signaling redox, 13 (9), 1309-1321.
[8][Adasankhidwa] [Cross Ref] Tabassum N., Hamdani M. (2014). Zomera zomwe zimagwiritsidwa ntchito pochiza matenda akhungu. Ndemanga za Pharmacognosy, 8 (15), 52-60
[9]Buggiani, G., Tsampau, D., Hercogovà, J., Rossi, R., Brazzini, B., & Lotti, T. (2012). Kuchita bwino kwazomwe zimachitika pamatenda a vitiligo: kuyerekezera kuyesa kwamankhwala osiyanasiyana mwa odwala 149. Datatologic therapy, 25 (5), 472-476.
[10]Gianfaldoni, S., Wollina, U., Tirant, M., Chernev, G., Lotti, J., Satolli, F.,… Lotti, T. (2018). Mankhwala Azitsamba Ochiza Vitiligo: Kuwunika. Tsegulani mwayi ku Makedoniya sayansi yamankhwala, 6 (1), 203-207.
[khumi ndi chimodzi]Moreira, C. G., Carrenho, L. Z. B., Pawloski, P. L., Soley, B. S., Cabrini, D. A., & Otuki, M.F (2015). Umboni wamankhwala am'mbuyomu a Pyrostegia venusta pochiza vitiligo. Journal of ethnopharmacology, 168, 315-325.
[12]Carlie, G., Ntusi, N. B. A., Hulley, P. A., & Kidson, S. H. (2003). KUVA (khellin kuphatikiza ma ultraviolet A) imathandizira kuchuluka ndi melanogenesis m'matenda a melanocytes amunthu komanso maselo a khansa ya khansa mu vitro. Briteni Journal of Dermatology, 149 (4), 707-717.
[13]Nestor, M., Bucay, V., Callender, V., Cohen, J. L., Sadick, N., & Waldorf, H. (2014). Polypodium leucotomos ngati Adjunct Treatment of Pigmentary Disorder. Journal of clinical and aesthetic dermatology, 7 (3), 13-17.