Mayeso Amwazi Atha Kuthandiza Kuzindikira Khansa ya M'mawere, Akutero Kafukufuku Waposachedwa

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Khansa ya m'mawere ndi mtundu wofala kwambiri wa khansa yopanda khungu. Amati ndi amodzi mwa mitundu yofala kwambiri ya khansa yomwe yakhudza anthu, makamaka mzaka 10 zapitazi. Ku India kokha, anthu opitilila 1 miliyoni amadwala khansa ya m'mawere chaka chilichonse.

Malinga ndi lipoti laposachedwa kwambiri, azimayi pafupifupi 252, 710 akuyembekezeredwa kuti akupezeka, ndipo azimayi pafupifupi 40,610 atha kufa ndi matendawa. Khansa ya m'mawere sikuti ndi akazi okha, chifukwa zimakhudzanso amuna. Anthu opitilira 9,500 amafuna chisamaliro cha khansa ya m'mawere chaka chilichonse ndipo pafupifupi anthu 1,500 amachitidwa opaleshoni ya khansa ya m'mawere chaka chilichonse ^[1] .

Khansa ya m'mawere imayamba m'maselo a m'mawere akamayamba kukula modabwitsa, omwe amachulukana mofulumira kuposa maselo athanzi ndikupitilizabe kuchulukana, zomwe zimapangitsa kukula kwa mtanda kapena chotupa ^[ziwiri] . Kawirikawiri, khansa ya m'mawere imapezeka pamene chizindikiro kapena chizindikiro chikuwonekera ndipo chimayesedwa mothandizidwa ndi mayeso ndi njira monga kuyesa mawere, mammogram , mawere a ultrasound etc.

Komabe, kafukufuku waposachedwa adati kuyezetsa magazi kwatsopano kungathandize kuzindikira khansa ya m'mawere koyambirira.

Kuyezetsa Magazi Kungakuthandizeni Kuzindikira Khansa Ya m'mawere Zaka 5 Zisanachitike Zizindikiro

Imodzi mwaziwopsezo zazikulu ndi zovuta zikafika ku khansa ndikuchedwa kuzindikira. Vutoli likafalikira kumadera ena, kupulumuka kumakhala kotsika kwambiri ndikuthekanso kubwereza ^[3] .

Komabe, kuzindikira msanga ndi chithandizo chothandiza kumathandizira kukonza zakufa. Koma pankhani ya khansa ya m'mawere, kuzindikira koyambirira kwachilengedwe kumakhala kochepa chifukwa nthawi zambiri sikumatulutsa zizindikilo zoyambirira, zomwe zimatha kuchititsa kuti munthu adziwe mochedwa zomwe zingakhudze chithandizo chamankhwala.

Kafukufuku waposachedwa omwe ochita kafukufuku ochokera ku University of Nottingham ku United Kingdom adatsimikiza kuti kuyesa magazi komwe kumawunika ma antibodies ena kungathandize kuzindikira khansa ya m'mawere msanga komanso mosavuta ^[4] .

Chiyeso Chitha Kuzindikira Ma Autoantibodies

Ofufuzawo anafotokozanso momwe magazi amayendera pofotokoza kuti khansa ikapezeka, thupi lanu limapanga ma antigen omwe amachititsa kuti chitetezo chamthupi chitengeke. Izi, zimapangitsa kuti chitetezo cha mthupi chitengeke ndi zinthuzo potulutsa ma autoantibodies, omwe adzawonekere poyesa magazi ndikuwonetsa ngati khansa ya m'mawere ilipo kapena ayi.

Poyamba, ofufuzawo adapanga magulu a ma antigen omwe amagwirizana ndi chotupa (TAAs) omwe amadziwika ndi khansa ya m'mawere yomwe imathandizira kumvetsetsa kupezeka kwa ma autoantigen m'magazi omwe amalumikizidwa ndi yankho la ma TAAs omwe amadziwika ndi khansa ya m'mawere. ^[5] .

M'modzi mwa ofufuzawo Daniyah Alfattani adati, 'Zotsatira za kafukufuku wathu zikuwonetsa kuti khansa ya m'mawere imapangitsa ma autoantibodies kuthana ndi ma antigen okhudzana ndi zotupa. Tidatha kuzindikira khansa molondola pozindikira ma autoantibodies m'magazi ', komanso tidatsimikiza zakufunika kokonza ndikuwunikiranso kuyesa magazi ^[6] .

Kafukufuku Akuwonetsa Zolonjeza

Ofufuzawa akusangalala ndi zotsatira za kafukufukuyu chifukwa zotsatira zake ndizolimbikitsa ndipo zikuwonetsa kuti ndizotheka kuzindikira chizindikiro cha khansa ya m'mawere yoyambirira. 'Tikangomaliza kuyesa kwa mayeso, zimatsegula mwayi wogwiritsa ntchito kuyesa magazi kosavuta kuti tizindikire matendawo msanga', anatero wofufuzayo ^[6] .

Phunziroli likakhala ndi anthu opitilira 90 omwe angafunsidwe, zitha kuganiziridwa kuti zotsatira zake ndizolondola ndipo kuyesa kwatsopano kwa magazi kumatha kukhala kothandiza pothandiza akatswiri azachipatala ndipo madotolo azindikira kupezeka kwa khansa ya m'mawere mpaka zaka 5 zisanachitike.

Pamapeto pake ...

Kafukufukuyu atapeza zotsatira zabwino, ofufuzawa akukulitsa gawo la kafukufukuyu chifukwa kuyesa magazi kuti adziwe khansa ya m'mawere koyambirira kungakhale kopanda ndalama, komanso kudzakhala kotheka komanso njira zosavuta zowunikira poyerekeza ndi njira zomwe zilipo kale ^[7] . Mayeso ofananawo akupanga mitundu ina ya khansa, kuphatikiza khansa yam'mapapu, kapamba, kolola, komanso khansa ya chiwindi.

1. [1]Lauren, S. & Cassell, M. Opaleshoni ya m'mawere, Lenox Hill Hospital, New York City Alice Police, MD, Westchester director director, opareshoni ya mawere, Northwell Health Cancer Institute, Sleepy Hollow, NY NCRI (National Cancer Research Institute, UK), kutulutsa nkhani, Novembala 2, 2019
2. [ziwiri]Spadafora, C., Sciamanna, I., De Luca, C., Sinibaldi-vallebona, P., Guadagni, F., Schumann, G., & Garaci, E. (2019). U.S. Kugwiritsa Ntchito Patent No. 15 / 564,089.
3. [3]Spadafora, C., Sciamanna, I., De Luca, C., Sinibaldi-Vallebona, P., Guadagni, F., Schumann, G., & Garaci, E. (2019). U.S. Kugwiritsa Ntchito Patent No. 10 / 214,591.
4. [4]Yadav, S., Kashaninejad, N., Masud, M. K., Yamauchi, Y., Nguyen, N. T., & Shiddiky, M. J. (2019). Ma autoantibodies monga matenda a khansa yozindikira komanso yolosera: Njira zodziwira ndi njira. Biosensors ndi Bioelectronics, 111315.
5. [5]Jiang, X. H., Yao, Z. Y., He, X., Zhang, J. B., Xie, K., Chen, J., ... & Yie, S. M. (2019). Kufunika kwazachipatala kwa anti-TOPO48 autoantibody ndi opulumuka m'magazi-omwe amafalitsa maselo a khansa mwa odwala omwe ali ndi gawo loyambirira la endometrial carcinoma. Zolemba zakale za azimayi azachipatala komanso azachipatala, 299 (1), 229-237.
6. [6]Seluk, L., Taliansky, A., Yonath, H., Gilburd, B., Amital, H., Shoenfeld, Y., & Kivity, S. (2019). Chowonekera chachikulu cha paraneoplastic neurological autoantibodies diagnostic and predictive values. Matenda a Immunology, 199, 29-36.
7. [7]Khayeka-Wandabwa, C., Ma, X., Cao, X., Nunna, V., Pathak, J. L., Bernhardt, R., ... & Bureik, M. (2019). Kakhungu kanyumba ka Plasma komwe kumayang'ana CYP4Z1 ndi CYP19A1 ndikuzindikira ma anti-CYP19A1 autoantibodies mwa anthu. International immunopharmacology, 73, 64-71.

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